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DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
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  • DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
  • DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
  • DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
  • DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
  • DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)

DERMA-CODE™ NAD+ • PDRN • Peptides Synergy Duo: Serum (1.01 fl oz) + Moisturizer (1.7 oz)
$149.00
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OVERVIEW

DERMA-CODE™ Synergy Duo

Facial Serum (1.01 fl oz) + Moisturizer (1.7 oz)

The DERMA-CODE™ Synergy Duo is a two-step performance skincare system designed to support visible improvements in texture, elasticity, hydration, and overall skin balance through complementary biological roles.

Rather than combining all actives into a single formula, the system is intentionally divided into two distinct products that work across different functional layers of the skin. The serum delivers concentrated actives to initiate visible signaling and surface refinement, while the moisturizer reinforces barrier stability, hydration balance, and sustained comfort.

Each formula is complete and effective on its own. When used together, they form a layered architecture that supports the skin’s natural renewal pathways without redundancy, overload, or cosmetic masking.

This system reflects the DERMA-CODE™ approach to formulation: precision over excess, biological alignment over short-term illusion, and transparency over marketing overlap.

What’s inside the Synergy Duo:

1. DERMA-CODE™ PDRN + NAD+ Facial Serum

A high-activity serum formulated with:

  • 2% PDRN (Sodium DNA)
  • 1% NAD+ (Nicotinamide Adenine Dinucleotide)
  • A targeted six-peptide network designed for visible refinement and signaling

Designed to support the appearance of smoother texture, improved elasticity, and energized skin response.

2. DERMA-CODE™ Universal Barrier Support Moisturizer

A barrier-focused moisturizer formulated with:

  • 1% PDRN (Sodium DNA)
  • 0.7% NAD+
  • A distinct six-peptide complex optimized for structural support and comfort

Designed to support hydration balance, barrier integrity, visible smoothness, and daily skin resilience.

Why the system works:

  • The serum initiates visible activity and targeted refinement
  • The moisturizer stabilizes, reinforces, and maintains the skin environment
  • Layering supports sustained improvement rather than short-term effects

The Synergy Duo is designed to work with the skin’s natural rhythm, not override it. Both products can be used independently or integrated seamlessly into an existing routine alongside compatible cleansers, moisturizers, and sunscreen.

Dermatologist tested and approved for general cosmetic use.

Contains ingredients sourced from salmon and soy. Avoid use if allergic.
THE BIOLOGY

DERMA-CODE™ is built on a biology-first skincare model grounded in Precision, Transparency, and Trust. Every molecule is selected for function, every concentration is intentional, and every mechanism is aligned with how skin actually operates. No fragrance. No dyes. No filler compounds.

The Synergy Duo is a two-formula system designed to work with the skin’s natural renewal rhythm at both the surface and barrier level. Each formula has a defined biological role. Together, they form a layered architecture that supports visible balance, resilience, and long-term skin integrity.

NAD+ (NAD Plus): Metabolic Balance and Skin Vitality

Nicotinamide Adenine Dinucleotide (NAD+) is a naturally occurring coenzyme involved in cellular metabolism and redox balance. As NAD+ levels decline with age, the skin’s ability to maintain visible vitality, manage oxidative stress, and preserve overall balance can diminish.

Both formulas contain stabilized NAD+ at meaningful cosmetic concentrations, expressed differently based on each product’s role.

In the Serum:

NAD+ is positioned within a high-activity system designed to support visible vitality, responsiveness, and surface renewal signaling.

In the Moisturizer:

NAD+ functions within a lightweight emulsion to support daily barrier equilibrium and sustained skin resilience.

Ingredient research supports NAD+ for:

  • Maintaining oxidative balance associated with visible skin vitality
  • Supporting the appearance of energized, resilient skin
  • Helping preserve barrier lipid balance related to NADP+/NADH cycling
  • Supporting the skin’s defense against environmental oxidative stress

PDRN: Renewal Signaling and Structural Support

Polydeoxyribonucleotide (PDRN) is a DNA polymer fraction derived from purified salmon DNA and used in cosmetic formulations as a nucleic-acid-based support ingredient in advanced renewal systems.

DERMA-CODE™ PDRN is refined to a low molecular weight range of approximately 50–300 kilodaltons (kDa), selected to support surface renewal and visible resilience.

In the Serum:

PDRN functions as a primary renewal-support signal, contributing to the appearance of smoother texture, elasticity, and refined skin quality.

In the Moisturizer:

PDRN supports ongoing surface comfort, hydration balance, and visible resilience within a barrier-supportive system.

At functional cosmetic concentrations, PDRN supports:

  • The appearance of smoother, more resilient skin
  • Improved look of texture and hydration
  • Visible comfort and balanced complexion
  • The appearance of elasticity and refined skin structure


Dual Peptide Network Architecture

The Synergy Duo does not rely on a single peptide system. Each formula contains a distinct peptide network engineered for its specific biological role.

Serum Peptide Network: Signal Initiation

The serum peptide system is designed to initiate visible signaling and surface refinement, supporting:

  • Expression line smoothing
  • Elasticity signaling
  • Visible clarity and refined texture

Moisturizer Peptide Network: Structural Reinforcement

The moisturizer peptide system is optimized for the maintenance phase, supporting:

  • Barrier stability and comfort
  • Skin density appearance
  • Structural balance without heaviness or occlusion

Together, these peptide networks form a multi-pathway communication system that supports visible firmness, smoothness, and overall skin balance.

Bio-Compatible Support Matrix

Both formulas are supported by a carefully balanced matrix of skin-identical and skin-supportive ingredients selected to enhance comfort, absorption, and compatibility.

Key components include:

  • Niacinamide to support barrier integrity and visible texture refinement
  • Squalane for lightweight, skin-identical moisture
  • Panthenol and Allantoin for surface comfort and sensitivity support
  • Sodium Hyaluronate for hydration balance
  • Tocopherol (Vitamin E) for antioxidant support
  • Lecithin to support ingredient stability and absorption
  • Hydroxyethylcellulose and Carbomer for lightweight structure without film buildup

Each ingredient is selected to support optimal absorption, comfort, and long-term skin balance.
HOW TO USE

Complete Two-Step System for Optimal Results

Step 1: DERMA-CODE™ Facial Serum
Apply 1–2 pumps to clean, dry skin after cleansing. Gently massage onto face and neck until fully absorbed. Allow 2-3 minutes for complete absorption before proceeding to Step 2.

Step 2: DERMA-CODE™ Facial Moisturizer
Apply a small amount of moisturizer to face and neck. For enhanced absorption, apply while skin is slightly damp from the serum application.

Timing & Frequency
Use morning and evening for optimal visible results. The system is designed to work with your skin's natural renewal cycle - consistency delivers the best outcomes.

Application Tips
• For sensitive skin: Start with evening use only, then gradually add morning application
• For dry skin: Apply moisturizer while skin is slightly damp for enhanced hydration
• For combination skin: Focus serum on areas needing extra support
• Allow full absorption between steps for maximum efficacy

Layering with Other Products
This duo is designed as a complete system but can be integrated with:
• Sunscreen (morning, after moisturizer)
• Gentle cleansers (before serum application)
• Compatible treatments as recommended by your skincare professional

Expected Timeline
Visible improvements in skin comfort and hydration may be noticed within days. Continued use supports progressive enhancement in the appearance of texture, elasticity, and overall skin quality over 4-8 weeks of consistent application.
TRANSPARENCY & INGREDIENTS

Ingredient Transparency

DERMA-CODE™ operates on full ingredient transparency. Every ingredient is disclosed using standard INCI terminology, and each concentration is selected for a defined biological function within the system.

SERUM – Full INCI List

Water (Aqua), Squalane, Niacinamide, Glycerin, Butylene Glycol, Pentylene Glycol, Caprylic/Capric Triglyceride, Propanediol, Sodium DNA, Nicotinamide Adenine Dinucleotide, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Octapeptide-3, Panthenol, Tocopherol, Allantoin, Sodium Hyaluronate, Lecithin, Hydroxyethylcellulose, Carbomer, Arginine, 1,2-Hexanediol, Ethylhexylglycerin, Disodium EDTA.

MOISTURIZER – Full INCI List

Water (Aqua), Glycerin, Squalane, Propanediol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Niacinamide, Pentylene Glycol, Butyrospermum Parkii (Shea) Butter, Dimethicone, Sodium DNA, Panthenol, Polysorbate 60, Phenoxyethanol, Nicotinamide Adenine Dinucleotide, Ceramide NP, Trehalose, Beta-Glucan, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Tocopherol, Ethylhexylglycerin, Sodium Hyaluronate, Cholesterol, Ceramide EOP, Carbomer, Hydroxyethylcellulose, Caprylhydroxamic Acid, Phytosphingosine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-8, Acetyl Heptapeptide-4, Oligopeptide-1, Heptapeptide-6, Acetyl Hexapeptide-8, Triethanolamine.

System Philosophy

DERMA-CODE™ formulas are engineered for biological performance, not cosmetic illusion. We formulate for visible skin improvement through purposeful ingredient selection and meaningful concentrations, not marketing constructs.

Built on Precision, Transparency, and Trust.

Transparency Note

DERMA-CODE™ products are cosmetic skincare. Ingredient science is provided for educational transparency and should not be interpreted as medical advice or treatment claims.

Caution

For external use only. Avoid direct contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.

Dermatologist tested and approved for general cosmetic use. Suitable for most skin types. Patch testing is recommended for extremely sensitive or allergy-prone skin.

Allergen Warning

Contains ingredients sourced from salmon and soy. Avoid use if allergic.
FAQS

WHAT IS THE SYNERGY DUO?

The DERMA-CODE™ Synergy Duo is a two-step biological skincare system consisting of the NAD+ • PDRN • 6-Peptide Facial Serum and the Universal Barrier Repair Moisturizer. The system is designed to support skin comfort, barrier integrity, and visible balance over time through coordinated formulation.

HOW DO I USE THE DUO?

Apply 1–2 pumps of the serum to clean, dry skin once or twice daily. Follow with a small amount of the moisturizer to support hydration and barrier comfort. Suitable for morning and evening use.

WHY USE BOTH PRODUCTS TOGETHER?

The serum provides concentrated bio-support at the skin surface, while the moisturizer reinforces barrier balance and hydration. Used together, they are designed to support consistent skin comfort and visible improvement over time.

WHEN WILL I SEE RESULTS?

Many users report improved hydration and skin texture within 1–2 weeks. More noticeable changes in overall skin appearance, smoothness, and comfort are commonly observed with continued use over 6–8 weeks. Individual results vary.

WHAT SKIN TYPES IS THIS SYSTEM FOR?

Suitable for most skin types, including dry, combination, mature, and sensitive skin. The formulas are designed to be lightweight, non-fragranced, and barrier-conscious.

CAN THIS SYSTEM BE USED AFTER PROFESSIONAL SKIN TREATMENTS?

Many clinicians and professionals choose this system as part of their post-procedure skincare routine once the skin is intact and no longer compromised. The formulas are fragrance-free and focused on barrier support and skin comfort. Always follow the guidance of your treating professional and wait until the skin is appropriate for cosmetic product use.

CAN I USE THE DUO WITH OTHER SKINCARE PRODUCTS?

Yes. The Synergy Duo is designed to integrate easily into existing routines and can be used alongside most cleansers, moisturizers, and sunscreen products.

IS THIS A MEDICAL OR PRESCRIPTION PRODUCT?

No. DERMA-CODE™ products are cosmetic skincare. Ingredient science is presented for educational transparency only and is not intended as medical advice or treatment.

WHERE CAN I LEARN MORE ABOUT THE SCIENCE?

Detailed ingredient and formulation information is available in the Science section, including discussions on NAD+ biology, PDRN molecular characteristics, and peptide signaling.

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