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DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
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  • DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
  • DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
  • DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
  • DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
  • DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump

DERMA-CODE™ NAD+ • PDRN • 6 Peptide SERUM - 1.01 fl oz (30ml) Airless Pump
$68.00 $67.33/oz
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OVERVIEW

DERMA-CODE™ NAD+ • PDRN • 6 Peptide Serum is a biologically aligned performance serum designed to support skin renewal, barrier integrity, and visible balance.

Formulated with 2% PDRN (Sodium DNA), 1% NAD+, and a coordinated six-peptide network, the system works at the level of cellular signaling, hydration regulation, and surface repair rather than short-term cosmetic effects.

Each ingredient is included at a functional concentration and selected for compatibility, stability, and cumulative skin response. No fragrance. No dyes. No filler compounds.

Produced in a GMP, FDA-registered facility and packaged in a protective airless system to preserve active integrity from first use to last.
THE BIOLOGY

DERMA-CODE™ products are built around skin biology, not cosmetic illusion. Every active is selected for biological relevance, functional concentration, and compatibility with the skin’s natural systems. The goal is cumulative skin stability, visible balance, and long-term barrier support rather than short-term surface effects.

NAD+ (NAD Plus): Cellular Energy and Repair Support

Nicotinamide Adenine Dinucleotide (NAD+) is an essential coenzyme involved in cellular energy production, DNA maintenance, and oxidative balance. As NAD+ levels decline with age and environmental stress, the skin’s ability to maintain energy, regulate oxidative processes, and support repair mechanisms is reduced.

Functions supported by ingredient research include:

  • Supporting cellular ATP energy production associated with renewal and vitality
  • Supporting DNA maintenance pathways involved in repair processes
  • Promoting balanced lipid and barrier activity through NADPH and NADH cycling
  • Helping defend against oxidative stress from environmental exposure

DERMA-CODE™ delivers stabilized NAD+ in meaningful concentrations to support bioavailability and visible skin balance over time.

PDRN: Molecular Support for Renewal

Polydeoxyribonucleotide (PDRN) is a DNA polymer fraction derived from salmon DNA fragments that act as nucleic-acid substrates and A2A receptor modulators.

The PDRN used in this formula is refined to a low molecular weight range of approximately 50 to 300 kilodaltons (kDa). This range is selected to support epidermal interaction and efficient biological signaling associated with visible regeneration and elasticity.

Supported skin benefits include:

  • Supporting fibroblast activity and collagen matrix organization
  • Promoting micro-circulation associated with improved tone and radiance
  • Helping calm visible irritation and maintain a balanced complexion
  • Improving the appearance of elasticity, hydration, and surface smoothness

At 2 percent, PDRN supports measurable improvements in hydration, density, and refined skin texture associated with healthier-looking, more resilient skin.

Six-Peptide Complex: Bio-Signal Architecture

This formula includes a coordinated network of six biomimetic peptides designed to support visible firmness and smoothness through cellular communication pathways.

The peptide network includes:

  1. Acetyl Hexapeptide-8, associated with visible smoothing of expression lines
  2. Palmitoyl Tripeptide-1, a collagen-fragment mimic that supports elasticity signaling
  3. Palmitoyl Tetrapeptide-7, associated with reducing the appearance of inflammation-related dullness
  4. Copper Tripeptide-1, supporting surface repair, clarity, and balanced texture
  5. Palmitoyl Pentapeptide-4, associated with dermal thickness and smoothness
  6. Acetyl Octapeptide-3, supporting surface relaxation effects related to deeper lines

Together, these peptides form a multi-pathway signaling system that supports visible firmness, smoothness, and overall skin balance.

Bio-Compatible Support Matrix

The active system is supported by barrier-aligned and skin-identical components selected for comfort, absorption, and compatibility.

Key support ingredients include:

  • Niacinamide, supporting barrier integrity and refined texture
  • Squalane, a skin-identical emollient delivering lightweight moisture
  • Panthenol and Allantoin, supporting surface comfort and calming sensitivity
  • Sodium Hyaluronate, binding hydration within the skin matrix
  • Tocopherol (Vitamin E), supporting defense against oxidative stress
  • Lecithin, supporting ingredient stabilization and absorption
  • Hydroxyethylcellulose and Carbomer, maintaining a lightweight gel structure without film buildup


Each component is included to support absorption, comfort, and overall skin balance while maintaining formula integrity.
HOW TO USE

Apply 1–2 pumps to clean skin after cleansing. Gently massage onto face and neck until fully absorbed. Use once or twice daily. For best results, follow with the DERMA-CODE™ NAD+ • PDRN • 6 Peptides Facial Moisturizer to seal in actives and reinforce barrier function.

Visible Performance

Visible changes associated with hydration, surface smoothness, and skin comfort.

• Skin appears more energized and luminous

• Texture feels smoother and more refined

• Elasticity and hydration look restored

• Fine lines and expression marks appear softened

With regular application, skin appears more balanced, firm, and visibly revitalized.

Results Over Time

DERMA-CODE™ formulas are designed to align with the skin’s natural renewal cycle rather than deliver immediate cosmetic masking. Consistent use supports visible improvement in smoothness, tone, and overall vitality that reflects true biological performance, not surface illusion.

With continued use, you can expect:

• Improved firmness and elasticity supported by PDRN and peptide synergy

• Refined texture through hydration support and cellular turnover alignment

• More even tone and luminosity through barrier optimization and NAD+ activity

• Increased comfort and resilience as skin regains natural balance

Results become more apparent with continued use, supporting genuine skin renewal rather than quick cosmetic cover-up.
INGREDIENTS

Full Ingredient List (INCI)


Water (Aqua), Squalane, Niacinamide, Glycerin, Butylene Glycol, Pentylene Glycol, Caprylic/Capric Triglyceride, Propanediol, Sodium DNA, Nicotinamide Adenine Dinucleotide, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Octapeptide-3, Panthenol, Tocopherol, Allantoin, Sodium Hyaluronate, Lecithin, Hydroxyethylcellulose, Carbomer, Arginine, 1,2-Hexanediol, Ethylhexylglycerin, Disodium EDTA.


Transparency Note


DERMA-CODE™ formulas are cosmetic skincare. Ingredient science is presented for educational transparency and should not be interpreted as medical advice or treatment claims.


Caution


For external use only. Avoid direct contact with eyes. Discontinue use if irritation occurs. Keep out of reach of children.

Dermatologist tested and approved for general cosmetic use. Suitable for most skin types. Patch testing is recommended for extremely sensitive or allergy-prone skin.


Allergen Warning


Contains ingredients sourced from salmon and soy. Avoid use if allergic
FAQs

What is NAD+ and why is it relevant for skin?

NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme involved in cellular energy production and repair processes. NAD+ levels decline with age, which can impact the skin’s ability to maintain balance, resilience, and recovery. This formula delivers stabilized NAD+ to support visible skin vitality and renewal.

What makes DERMA-CODE™ PDRN different?

DERMA-CODE™ uses low-molecular-weight PDRN (50–300 kDa) derived from salmon DNA. This size range is selected for compatibility with the skin barrier and efficient biological signaling, supporting visible renewal, hydration, and texture refinement without irritation.

How do I use the serum?

Apply 1–2 pumps to clean skin once or twice daily before moisturizer. Gently massage over face and neck until fully absorbed. The airless pump helps preserve ingredient stability and potency.


Can this be used post-procedure?

Yes. The serum is commonly used after professional treatments such as chemical peels, laser, or microneedling once the skin is intact and cleared by the provider. Its barrier-supportive, fragrance-free formulation makes it suitable for post-procedure routines focused on comfort, hydration, and visible recovery. Always follow your provider’s specific post-care instructions.

When will I see results?

Many users notice improvements in skin texture and hydration within 2–3 weeks. Continued use supports visible gains in smoothness, firmness, and overall skin balance over time as part of a consistent routine.

Can I use this with other products?

Yes. The serum layers well with most skincare routines. For a complete DERMA-CODE™ system, follow with the DERMA-CODE™ NAD+ • PDRN • 6 Peptide Facial Moisturizer to support barrier integrity.

Where can I learn more about the formulation science?

Additional information on NAD+, PDRN, and peptide networks is available on the DERMA-CODE™ Science and Proof & Integrity pages.

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Learn more about our commitment to quality and transparency on our Proof and Integrity page, where you can access third-party testing certificates, ingredient verification documents, and manufacturing compliance reports.